Journal Club 18: Anorexia Nervosa
Psychiatry Education Forum Academy is excited to announce the released date for our 17th journal club discussion. This journal club will focus on this clinically…
Author: Dr. Harvinder Singh
Autism Spectrum Disorder: Agitation, Irritability & Sensory Sensitivity Management
We know that medications are not the first-line treatment for autism spectrum disorder (ASD) management but they are helpful when first-line behavioral interventions are not…
Can Suvorexant help with Chronic Insomnia?
According to the International Classification of Sleep Disorders (Third Edition), Insomnia is defined as: either trouble initiating or maintaining sleep, associated with daytime consequences, and…
Can Depakote help with Delirium?
Delirium is one of the most commonly encountered psychiatric diagnosis in the hospital setting. Untreated delirium can have significant negative effects on patients’ morbidity and…
Restless Leg Syndrome: How to Diagnose, Evaluate & Treat
Restless leg syndrome is a common neurological condition, which can be easily missed or misdiagnosed as insomnia. On the other hand, most antidepressants and antipsychotics…
Managing Treatment Resistant Depression with Atypical Features
Depression with atypical features is defined as significant mood reactivity combined with two of the following clinical features: Hyperphagia Hypersomnia Leaden paralysis Pathological rejection sensitivity…
Integrative and Complementary Psychiatry
Psychiatry Education Forum Academy released the next lecture series for our academy members, where Dr. Harvinder Singh will discuss the following clinically relevant topics from…
Can St. John’s Wort help with Depression?
Psychiatry Education Forum Academy is excited to announce our next presentation’s release date for Sep 10, 2022: WATCH INTRODUCTION VIDEO https://youtu.be/Q01KwQTdTqM There are many plant-based…
Predictors of Suicidal Ideation after Stroke?
Post-stroke depression is considered one of the common neuropsychiatric complications of cerebrovascular stroke, affecting approximately one third of stroke survivors at any one time after…
Auvelity: New Oral Fast Acting FDA Approved Antidepressant
On Aug 19, 2022 Axsome Therapeutics announced the FDA Approval of Auvelity, as the first and Only Oral NMDA Receptor Antagonist for the treatment of…
Managing Clozapine’s Adverse Events
Clozapine was FDA-approved for treatment-refractory schizophrenia in 1989 and has remained the gold standard treatment since then for this indication. Clozapine has established efficacy in…
How to Evaluate Six Neurocognitive Domains in Dementia: Social Cognition
It is important to have knowledge of these six neuro-cognitive domains for the evaluation & diagnosis of dementia subtypes. In this discussion series, Dr. Harvinder…
Lamotrigine Dosing in Pregnancy & Postpartum
Let’s begin by answering this question first: Answer: Gradual increase in dose from first to third trimester; and dose taper within three days of delivery…
Postpartum Psychosis Management?
Postpartum psychosis is a psychiatric emergency that warrants immediate treatment, including admission to ensure the safety of mother and baby. Understanding the treatment algorithm for…
OCD Psychopharmacology Algorithm: 3 Days Lecture Series
Psychiatry Education Forum Academy is announcing our next lecture series, where Dr. David Osser will discuss the psychopharmacology algorithm project’s recent update on the psychopharmacological…
Low Testosterone Level & Depression: Should you check?
Psychiatry Education Forum Academy is excited to announce the release of our 17th journal club discussion. This journal club will focus on this clinically relevant…
Safer Antidepressants with Bleeding Risk?
BEFORE SCROLLING DOWN ==> SUBMIT YOUR ANSWERS FIRST 🙂 . . . . What is the Underlying Mechanism? SSRIs limit uptake of blood serotonin by…
ADHD & Depression: Important Drug Interactions
This question is more directed toward drug-drug interactions and the role of Cytochrome P450: Atomoxetine is metabolized by CYP2D6, so we should avoid medications inhibiting…
Serious Rashes Associated with Mood Stabilizers
Psychiatry Education Forum Academy is excited to announce the following coffee club discussion: SERIOUS RASHES ASSOCIATED WITH MOOD STABILIZERS Presentation by: Dr. Satinder Pal Kaur,…
Medications Affecting Clozapine Level?
Clozapine is indicated for the management of treatment resistant schizophrenia and hence it is likely that patient will also be taking other psychotropic and non-psychotropic…
Varenicline: How to Dose?
According to this article (Expert Opin Drug Discov. 2018;13(7):671-683), people who try to quit nicotine smoking: 80% return to smoking within the first month <…
FDA Authorized Diagnostic Aid for Autism Spectrum Disorder
Autism spectrum disorder (ASD) is one of the most common developmental disorders. The importance of early ASD diagnosis is of clinical importance, as early interventions…
Can Silexan help with Anxiety?
Silexan is a standardized essential oil of L. angustifolia flowers prepared by steam distillation. This is currently approved in Germany for the management of restlessness…
Steroids Induced Psychiatric Side Effects
STEROIDS & NEUROPSYCHIATRIC ADVERSE EVENTS Neuropsychiatric Adverse Events from Non-Psychiatric Medications Patients on higher doses of steroids can present with affective, behavioral, and cognitive symptoms.…
Gingko Biloba for Antidepressants Induced Sexual Dysfunction?
Can Ginkgo Biloba help with antidepressant-induced sexual dysfunction? WHAT IS THE LIKELY MECHANISM OF ACTION: Prostaglandin synthesis and vasodilation ==> resulting in increase peripheral blood…
Managing Aggression after Traumatic Brain Injury
Traumatic brain injury can significantly impact an individual’s life, in terms of cognitive, behavioral, and physical impairments. Among these, aggression remains the most challenging for…
Omega-3 Fatty Acids for Depression?
Recently Omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) have drawn the clinical attention for the treatment of major depressive disorder. The…
Journal Club 16: Lithium use during Pregnancy & Postpartum
Psychiatry Education Forum Academy is excited to release our 16th journal club discussion today. This journal club will focus on this clinically relevant topic of…
OCD: When to Discontinue Treatment?
Let’s begin by answering this question first: APA 2007 guideline recommends that successful medication treatment for OCD be continued for 1–2 years before considering a…
Binge Eating Disorder: Diagnose & Treatment?
Lifetime prevalence estimates of DSM-IV anorexia nervosa, bulimia nervosa, and binge eating disorder are .9%, 1.5%, and 3.5% among women, and .3% .5%, and 2.0%…
Lithium Adverse Events Management
Psychiatry Education Forum Academy just finished the lecture series on Understanding Lithium’s Adverse Events Management. Here we have discussed the clinical details of how to…
Lithium & Gastrointestinal Side Effects
We continue our lecture series on Lithium Adverse Events Management with the discussion of Lithium Induced Gastrointestinal side effects. Nausea and/or diarrhea are common gastrointestinal…
Lithium Induced Hyperparathyroidism
We continue our lecture series on Lithium Adverse Events Management with the discussion of Lithium Induced Hyperparathyroidism. The first case of Lithium induced hyperparathyroidism was…
Lithium Induced Hypothyroidism
We continue our lecture series on Lithium Adverse Events Management with the discussion of Lithium Induced Hypothyroidism. The antithyroid effects of lithium were recognized in…
Lithium Induced Tremors
We continue our lecture series on Lithium Adverse Events Management with the discussion of Lithium Induced Tremors. Tremors are one of the common side effects…
Lithium Induced Polyuria
Lithium is the oldest mood stabilizer approved for bipolar disorder and still is considered the gold standard treatment. Lithium is not protein bound, is not…
Viloxazine: Non-Stimulant Medication now FDA Approved for Adult ADHD
Viloxazine ER (Qelbree) was initially approved for pediatric ADHD and now had received FDA approval for the management of ADHD in adult patients. We have…
Lithium Adverse Events Management: Academy’s Lecture Series
A patient in his mid 30s was brought to the hospital by police for increased aggression towards his family members. On evaluation he reported a…
Lumateperone Two New Dosages Approved: 21 mg & 10.5 mg
Lumateperone received its first FDA approval for the management of adult schizophrenia in 2019, and recently FDA has just approved this medication for depressive episodes…
Can Gabapentin help with Alcohol Withdrawal Management?
Gabapentin is currently FDA approved for restless leg syndrome, partial-onset seizures, and postherpetic neuralgia. Although not a first-line medication, recently many studies have shown gabapentin…
Trazodone: Basics & Beyond
This post will summarize Trazodone’s mechanism of action and answer the following two questions: What dose of Trazodone is effective for major depression disorder (MDD)…
Urine Drug Test: Phencyclidine
Phencyclidine abuse can cause violent and aggressive behaviors, severe hallucinations, paranoia, and impaired motor skills. Few medications can cause false-positive results can occur for agents…
Urine Drug Tests: Amphetamines
Amphetamine screening tests are most commonly associated with false positive tests and this includes false positive results from psychotropic medications as well. Let’s begin by…
Urine Drug Tests: Benzodiazepines
LECTURE SERIES DAY 3: RELEASED TODAY We continue our lecture series on the “Clinical Interpretation of Urine Drug Tests” with a discussion on the following…
Urine Drug Screen: Opioids
LECTURE SERIES DAY 2: RELEASED TODAY We continue our lecture series on the “Clinical Interpretation of Urine Drug Tests” with a discussion on the following…
Urine Drug Screen: Cannabinoids
LECTURE SERIES DAY 1: RELEASED TODAY Today we begin this clinically relevant lecture series for our academy members with videos on the following two topics:…
IGALMI™ (Dexmedetomidine): First Sublingual Medication FDA Approved for Acute Agitation
Today FDA has approved the first sublingual medication, IGALMI (Dexmedetomidine) for the management of acute agitation in indications discussed below. We have summarized this medication…
Clinical Interpretation of Urine Drug Tests: Journal Club 15
Psychiatry Education Forum Academy has released the complete lecture schedule for our academy members today: CLINICAL INTERPRETATION OF URINE DRUG TESTS It is important to…
Managing Severe Melancholic Depression
Melancholic features in major depressive disorder are characterized by: ONE of the following present during the most severe period of the current episode: Loss of…
Valproate Induced Tremors
Valproate is considered the first-line medication for bipolar disorder management but is known to cause various adverse events. Among these adverse events, tremors are one…
First Weekly Transdermal Patch Approved for Alzheimer’s Dementia: ADLARITY
On March 14, 2022: FDA has approved the first and only once-weekly transdermal patch for Alzheimer’s dementia: Adlarity (Donepezil). Psychiatry Education Forum Academy has summarized…
Parkinson’s Disease & Impulse Control Disorders
Psychiatry Education Forum Academy’s lecture series on “Impulse Control & Self Injurious Behaviors: Pharmacological Management” has released the next lecture today: Parkinson’s Disease & Impulse…
Naltrexone for Impulse Control Management?
Psychiatry Education Forum Academy (PEFA) is excited to announce our next lecture series on “Impulse Control & Self Injurious Behaviors: Pharmacological Management”. Today we released…
Academy Post Summary: Feb 2022
In February 2022, Psychiatry Education Forum Academy added the following 6 clinically relevant chapters. Please let me know if you found them clinically relevant. (1)…
Can NAC help with Cannabis Use Disorder?
Cannabis is one of the commonly used illicit substances. The use has increased further with multiple states legalizing cannabis use in the United States. Cannabis…
Antidepressant Induced Excessive Sweating
Antidepressant-induced excessive sweating (ADIES) is reported in more than 20% of patients taking antidepressants. For this reason, the knowledge on how to identify and manage…
Journal Club 14: Dose-Response Meta-Analysis of Antipsychotics for Acute Schizophrenia
Psychiatry Education Forum Academy is excited to release our next journal club discussion today. This journal club will focus on this clinically relevant topic of…
Journal Club’s New Feature: ABCC Pathway Track
Psychiatry Education Forum’s Journal Club is an additional feature for our Academy’s members. We are excited to announce the release of our new feature in…
Antidepressant use during Lactation?
BEFORE SCROLLING DOWN ==> SUBMIT YOUR ANSWERS FIRST 🙂 Antidepressant treatment is indicated for post-partum depression. For this reason, it is of direct clinical relevance…
Chronic Insomnia Pharmacological Treatment: Practice Guideline
According to the International Classification of Sleep Disorders (Third Edition), Insomnia is defined as: either trouble initiating or maintaining sleep, associated with daytime consequences, and…
Chronic Benzodiazepine Discontinuation: Pharmacological Options
Although benzodiazepines are only indicated for short-term prescription use, a certain percentage of patients can end up on the long-term use resulting in both physiological…
Serotonin Syndrome: 5 Clinical Facts
Serotonin syndrome is considered a psychiatric emergency, characterized by excess of serotonin in central nervous system, which if severe can become life threatening. We have…
Ulipristal Acetate for PMDD Treatment?
Share This Post Share on facebook Share on linkedin Share on twitter Share on email Close to 70-90 % of reproductive age women are known…
New Sleep Medication Approved: Daridorexant (Quviviq)
On Jan 10, 2022, FDA has approved this new medication for treatment of adults with insomnia: Quviviq (daridorexant). This FDA approval is based on the…
Top 5 Viewed Posts in 2021
On this last day of 2021, let’s review our top 5 viewed posts of this year: Bipolar Disorder Psychopharmacology (1) Restarting Lamotrigine after abrupt Discontinuation…
Comparing FDA Approved Bipolar Depression Medications
Depression in bipolar disorder is considered the most common mood phase and also a major clinical challenge. This is known to cause impairment from being…
Lumateperone: Newest FDA Approved Medication for Bipolar Depression
Dec 20, 2021. We know that Lumateperone received its first FDA approval for the management of adult schizophrenia in 2019, but FDA has just approved…
Antipsychotics, High Prolactin Level & Risk of Breast Cancer
Today, we released the journal club #13 for our psychiatry education forum academy members. This journal club will compare the findings of this 2014 study…
Anti-NMDAR Encephalitis: What should you know as a Psychiatrist?
Anti-NMDA Receptor Encephalitis This is an autoimmune disorder in which antibodies attack NMDA (N-methyl D aspartate) type glutamate receptors at central neuronal synapses. Psychiatrists should…
Comparing Serotonin Modulators: Vortioxetine vs Vilazodone
Serotonin modulators are a class of medications approved for the treatment of the major depressive disorder. Psychiatry Education Forum Academy’s recent chapter will compare these…
Antidepressants use with Hepatitis C?
BEFORE SCROLLING DOWN ==> SUBMIT YOUR ANSWERS FIRST 🙂 According to this review article published in BMC Gastroenterology: Level 1 Evidence is based on ≥…
Antipsychotic of choice for “Schizo-Obsessive” Disorder?
BEFORE SCROLLING DOWN ==> SUBMIT YOUR ANSWERS FIRST 🙂 There is growing evidence that patients with comorbid obsessive-compulsive disorder (OCD) and schizophrenia may represent a…
Ginkgo Biloba for Antidepressants Induced Sexual Dysfunction
Can Ginkgo Biloba help with antidepressants induced sexual dysfunction? MECHANISM OF ACTION: Prostaglandin synthesis and vasodilation ==> resulting in increase peripheral blood flow and to…
Lithium Induced Diabetes Insipidus: Prevention & Treatment
Lithium is considered the gold standard and first-line treatment for bipolar disorder and is known to have adverse effects on the kidney, thyroid, parathyroid, neurological…
Comparing Long-Acting Methylphenidate: Concerta vs Jornay PM vs Adhansia XR
Attention-deficit/hyperactivity disorder (ADHD) is a common and impairing disorder affecting children, adolescents, and adults. Stimulant class of medications are considered first-line treatment for ADHD, including…
What Features Differentiates Bipolar Depression from MDD?
Q: What Features Differentiate Bipolar Depression from MDD? Bipolar depression is characterized by significantly higher rates of: Psychomotor retardation Difficulty thinking Early morning awakening, morning worsening…
Antidepressant with Renal Impairment?
A 43-year-old male with a history of major depressive disorder is referred to you by his primary care physician for management of depression with the…
How Long to Continue Antidepressants for MDD Treatment?
Once you have initiated antidepressants for MDD (Major Depressive Disorder) treatment and the patient has achieved remission, how long will you continue this current antidepressant…
ADHD Medications with Breastfeeding?
ADHD is a common neurobehavioral disorder that can persist into adulthood and treatment can have a significant positive impact on a person’s daily functioning. ADHD…
Bupropion & Risk of Seizures
With the IR formulation, the rate is 0.4% (4/1000) at doses of 300 to 450 mg/day. With the SR formulation, the rate is 0.1% (1/1000)…
Venlafaxine vs Duloxetine: How are they different?
SNRIs: Venlafaxine vs Duloxetine © Psychiatry Education Forum FOR ACADEMY MEMBERS: (1) SNRI use with RENAL impairment This chapter will summarize the dosage adjustment of…
L-Methylfolate for Depression: When to use?
L-MethylFolate is used as an augmentation agent to antidepressants in patients with major depression disorder, but who is a good candidate for considering L-Methylfolate as…
Can we use Lamotrigine with Oral Contraceptives?
The drug interaction between Lamotrigine and Oral Contraceptives is of direct clinical relevance for your daily clinical practice. This topic is summarized in the following…
Bipolar Disorder with Mixed Features: Update 2021
Bipolar disorder is a chronic mood disorder associated with various mood states including mania, hypomania, depression, and mixed states. The identification and treatment of mixed…
Augmentation Strategies for Clozapine-Resistant Schizophrenia?
Clozapine is considered a gold-standard medication for treatment-resistant schizophrenia, but close to 50% of these patients on clozapine may show poor or no response. What…
Is Bupropion Effective for Anxiety Disorder (GAD)?
Generalized Anxiety Disorder (GAD) is a common psychiatric disorder with chronic waxing and waning course for some. Serotonergic medications (SSRIs and SNRIs) are considered first-line…
Valproate Adverse Events Management
Valproate is considered first-line treatment for the management of bipolar disorder with the following recommendations per recent CANMAT & ISBD 2018 guidelines: Acute Mania: First…
Geriatric Psychiatry: Neurocognitive Disorders [PEFA Discussions]
Alzheimer’s disease is the most common type/cause of dementia. As we know that FDA recently approved Aducanumab (Aduhelm) for the treatment of Alzheimer’s Disease (read…
Treatment-Resistant MDD: Modafinil Augmentation
Partial response, no response, or residual symptoms following antidepressant therapy is common in clinical psychiatry. Hence, it is of clinical importance to have knowledge of…
Safest Antidepressant with Warfarin?
Answer: (b) Sertraline. Warfarin has two isomers: S-isomer (three times more potent than R-isomer): metabolized by 2C9. R-isomer: metabolized by 1A2 (major) and 2C19 & 3A4 (minor) —> monitor…
How to use Pramipexole for Bipolar Depression?
Pramipexole is currently only FDA approved for Parkinson’s disease & Moderate-to-severe primary Restless Legs Syndrome but Pramipexole has promising data as an augmentation option for…
Emotional Blunting with Antidepressants Versus Anhedonia from MDD?
Antidepressants are well known to cause this side effects of emotional blunting. It is clinically relevant to diagnose this early in the treatment as this…
Invega Hafyera™ (6-monthly paliperidone palmitate): FDA Approved for Schizophrenia
Sep 01, 2021. Today FDA approved the first and only 6 monthly long-acting injectable for schizophrenia treatment: Invega Hafyera. We have summarized Invega Hafyera clinical…
Topiramate & Cognitive Dulling
Topiramate is well known to cause cognitive dulling and patients should use caution when operating machinery including automobiles. How can we prevent the risk of…
Testosterone & Depression in Men?
Age-associated hypogonadism (testosterone deficit) can occurs in 30% of men after the age of 55 (1). Low testosterone is associated with decreased muscle mass, bone…
How to Screen for Delirium Superimposed on Dementia?
When delirium and dementia coexist: this is referred to as delirium superimposed on dementia (DSD). Delirium and dementia are associated with: lengthier hospital stays functional…
Mood Stabilizers Use During Pregnancy & Postpartum
The perinatal period can increase the risk of mood symptoms recurrence for patients with bipolar disorder, including the risk of depressive episode recurrences and postpartum…
How to Differentiate Obsessions from Delusions?
The presence of obsessive-compulsive symptoms (OCS) and obsessive-compulsive disorders (OCD) in schizophrenia is frequent. It is of clinical relevance to separate obsessive symptoms from delusional…
Antidepressant & Tamoxifen use in Breast Cancer?
Depression and anxiety are common comorbidities in breast cancer patients. As a results patients with breast cancer may require treatment with antidepressants. For this reason,…
Attention PEFA Members: Join PEFA Network
Dear PEFA Members. We are excited to release a new update in our academy: PEFA Network. This is a closed group for PEFA members only and…
Antipsychotics & risk of Hypersexual or Paraphilic Behaviors
We know that dopamine agonism can result in hypersexual or paraphilic behaviors but interestingly, case reports for second-generation antipsychotics association with increase in hypersexual behavior…
Traumatic Brain Injury: Management Series [PEFA]
The risk for psychiatric disorders and symptoms can increase after the traumatic brain injury, and long-term disability from TBI has primarily been attributed to neurobehavioral…
Clomipramine for Pediatric OCD?
We know that CBT and SSRI are considered first-line treatments for pediatric OCD management, but few patients are treatment-refractory and they do not respond to…
Cyproheptadine for PTSD Nightmares
The diagnosis of PTSD requires the endorsement of one of two symptoms from the symptom clusters of (1) reexperiencing, (2) avoidance, and (3) sense of…
Memantine for Treatment-Resistant OCD
OCD is a chronic neuropsychiatric disorder that can cause significant psychosocial impairment (Goodman et al., 2021), and delay in treatment is associated with poor outcomes…
Message Each Other: New PEFA Feature
Today we are excited to announce the release of our website’s new feature for PEFA members. Now PEFA members can message each other privately to…
Clomipramine Therapeutic Level
Therapeutic Drug Monitoring (TDM) of psychotropic medication is a clinically relevant topic as TDM can be a beneficial test in following clinical scenarios checking medication…
Antipsychotics Induced Edema
Antipsychotic-induced edema is not an uncommon side-effect. In most cases, this can be a transient and self-limited side effect but it is important to know…
How to Evaluate Six Neurocognitive Domains in Dementia? [PUBLISHED]
Psychiatry Education Forum Academy published its next discussion series today: It is important to have knowledge of these six neuro-cognitive domains for the evaluation &…
How to Evaluate Six Neurocognitive Domains in Dementia?
Today we are excited to announce Psychiatry Education Forum Academy’s next discussion with release date for this Saturday (July 24): It is important to have…
Autism Spectrum Disorder: Aggression & Irritability Management
We know that medications are not the first-line treatment for autism spectrum disorder (ASD) management but they are helpful when first-line behavioral interventions are not…
Psycho-Ophthalmology: Psychotropics Ocular Adverse Events
Psychotropic medications are known to cause ocular side effects. We have a detailed section on this topic in Psychiatry Education Forum Academy. Let’s begin with…
Alzheimer’s Disease: Comparing FDA Approved Medications
Alzheimer’s disease is the most common type/cause of dementia. As we know that FDA recently approved Aducanumab (Aduhelm) for the treatment of Alzheimer’s Disease (read…
[PEFA Journal Club]: Claim 4.75 CME Credits
We just finished our 13 journal club discussions at PEFA (Psychiatry Education Forum Academy). PEFA members can claim a maximum of 4.75 AMA PRA Category…
[Journal Club 13 + Coffee Club]: International Trauma Questionnaire (ITQ) for PTSD & CPTSD
Today we posted the following 13th journal club in PEFA Journal Club’s discussion series and discussion with an expert in our Coffee Club’s discussion section:…
[Journal Club #12 + Coffee Club]: Is Ketamine Safe with History of Psychosis?
Today we posted the following 12th journal club in PEFA Journal Club’s discussion series and discussion with an expert in our Coffee Club’s discussion section:…
[Journal Club 11 + Coffee Club]: Benzodiazepines & Risk of Subsequent Dementia?
Today we posted the following 11th journal club in PEFA Journal Club’s discussion series and discussion with an expert in our Coffee Club’s discussion section:…
[Journal Club #10]: Antipsychotics & Weight Gain
Today we posted our 10th journal club in PEFA Journal Club’s discussion series, discussing the risk of weight gain with antipsychotics: Journal Club #10: Almost…
[Journal Club #9 + Coffee Club]: Adjunctive Metformin for Antipsychotic-Induced Dyslipidemia.
Today we posted the following 9th journal club in PEFA Journal Club’s discussion series and discussion with an expert in our Coffee Club’s discussion section:…
[Journal Club #8]: Is Vortioxetine Effective for Emotional Blunting in MDD?
Today we posted the eighth journal club in PEFA Journal Club’s discussion series, discussing if Vortioxetine is effective for emotional blunting in MDD after inadequate…
[Journal Club #6 + #7]: Two New Schizophrenia Medications with Novel Mechanism of Action
Today we posted the sixth and seventh journal club in PEFA Journal Club’s discussion series, discussing the following two newer antipsychotics for schizophrenia treatment: (A)…
[Journal Club #5 + Coffee Club]: Comparing 32 Oral Antipsychotics for Acute Schizophrenia Management.
Today we posted the following fifth journal club in PEFA Journal Club’s discussion series and discussion with a expert in our Coffee Club’s discussion section:…
Journal Club #4: How Does Schizophrenia Symptoms Progress with Age?
Today we posted the following fourth journal club in PEFA Journal Club’s discussion series: Journal Club #4: Staging of Schizophrenia With the Use of PANSS:…
Journal Club #3: Bipolar Depression Guidelines: CANMAT & ISBD Versus Psychopharmacology Algorithm Project
Today we posted the following third journal club in PEFA Journal Club’s discussion series: Journal Club #3: The Psychopharmacology Algorithm Project at the Harvard South…
Journal Club #2: Omega-3 Fatty Acids for MDD Treatment (ISNPR Practice Guidelines)
Today we posted the following second journal club in PEFA Journal Club’s discussion series: Journal Club #2: International Society for Nutritional Psychiatry Research Practice Guidelines…
Journal Club #1: Update on Nonpsychotic Unipolar Depression Management
We begin PEFA Journal Club’s updated schedule with our first journal club discussion today: Journal Club #1: The Psychopharmacology Algorithm Project at the Harvard South…
PEFA Journal Club: Updated Schedule Released
Psychiatry Education Forum’s Journal Club is an additional feature for PEF Academy’s members. All academy members will be automatically enrolled in this journal club. Here…
Antipsychotics of Choice during Lactation
Antipsychotics of Choice During Lactation: This PEFA academy chapter will summarize the use of antipsychotics during lactation in the following sections: FIRST-LINE treatment options during…
Aducanumab: New Medication FDA Approved for Alzheimer’s Disease
June 07, 2021 Today FDA has approved Aducanumab (Aduhelm) for the treatment of Alzheimer’s Disease. This is the first novel treatment to target the underlying…
LYBALVI™: New Medication FDA Approved for Schizophrenia & Bipolar Disorder
June 01, 2021 Today FDA approved LYBALVI for the treatment of: Schizophrenia in adults Bipolar I disorder in adults Acute treatment of manic or mixed…
PEFA Newsletter: May 2021
PSYCHIATRY EDUCATION FORUM ACADEMY’S NEWSLETTER MAY 2021 Here is the summary of topics posted in the month of May at Psychiatry Education Forum Academy. These…
How do Schizophrenia Symptoms Progress over 40 years?
Today (May 24) is World Schizophrenia Day. The purpose of this day is to increase awareness and reduce the stigma associated with the diagnosis of…
How to Switch Between Valproate Formulations?
Valproate is an FDA approved treatment for bipolar disorder. According to CANMAT and ISBD (2018 guidelines) valproate is indicated for the following phases of bipolar…
Psychological Approaches for Auditory Hallucinations Management
Antipsychotic medications are commonly used to treat auditory hallucinations but it is equally important to teach patients these psychological skills to reduce the distress associated…
Benztropine or Glycopyrrolate: Which one is preferred for Antidepressants Induced Sweating?
Glycopyrrolate is preferred over Benztropine for the following reasons: for Glycopyrrolate is less known to cross the blood-brain barrier, hence less central adverse events (less…
Medications vs Psychotherapy for MDD: Comparing 5 Major Guidelines
How do you decide between psychotherapy versus medications for the treatment of major depressive disorder? Depression severity is one of the criteria used to make…
Psychotropics & Risk of Tinnitus
Tinnitus is defined as the conscious awareness of a sound in the absence of an external auditory stimulus. Psychotropic medications are commonly used as the…
Naltrexone XR: When & How to Initiate?
Naltrexone XR is an opioid antagonist, which is FDA approved for opioid use disorder. The main benefits of naltrexone-XR are: extended duration of its action…
Pseudobulbar Affect: Identify & Manage
Psychiatry Education Forum Academy’s Coffee Club contains short discussions with clinical experts in the field of psychiatry. Coffee Club’s goal is to get answers for clinically…
Lumateperone: Mechanism of Action?
Lumateperone is the most recently approved FDA-approved medication for the treatment of schizophrenia. Watch the following short video discussion from our journal club regarding the…
How to Diagnose PMDD?
Premenstrual disorders can range from mild premenstrual syndrome (PMS) to premenstrual dysphoric disorder (PMDD). It is known that close to 70-90 % of reproductive age…
Lithium Induced Polyuria: Laboratory Evaluation
Watch the following short 5 minutes video from Psychiatry Education Forum’s Bipolar Disorder Update 2020 Conference. This video will briefly discuss the important laboratory workup…
Psychiatry Education Forum Featured on Psychiatric News.
Thanks to Psychiatric News for covering Psychiatry Education Forum’s Bipolar Disorder Update 2020 Conference. Here is Dr. Harvinder Singh’s interview on Bipolar Disorder Mixed Features:…
Treatment-Resistant GAD: 8 Augmentation & 12 Switching Options
Psychiatry Education Forum Academy will publish a detailed lecture on the management options for treatment-resistant GAD (Generalized Anxiety Disorder) tomorrow: April 18 (Sunday). This detailed…
Genetic Testing in Psychiatry: MTHFR & L-MethylFolate
MTHFR gene encodes for MethyleneTetraHydroFolate Reductase (MTHFR) enzyme. It is important to have the knowledge of the following two MTHFR polymorphisms for you to interpret…
GAD: Initial Medication of Choice?
Generalized Anxiety Disorder (GAD) is a common psychiatric disorder with chronic waxing and waning course for some. Psychiatry Education Forum Academy will summarize the pharmacological…
Transdermal Asenapine
ANSWER: (d) All of the above. Apply to a different application site each time a new transdermal system is applied. Do not cut the patch.…
PEF Clinical Fact: Antipsychotic of Choice in COVID & Pneumonia
INTERESTED IN LEARNING MORE? JOIN PSYCHIATRY EDUCATION FORUM ACADEMY MEMBERSHIP This educational activity is dedicated to the essential and must-know clinical facts regarding the interaction…
Restless Legs with Antidepressants?
Restless leg syndrome is defined as having following four essential clinical consensus criteria: (a) Compelling urge to move the legs with or caused by uncomfortable…
Can L-Theanine Help with Anxiety Management?
Share this post Share on facebook Share on google Share on twitter Share on linkedin Share on pinterest Share on print Share on email L-theanine…
Is Olanzapine Effective for Bipolar Mixed Features Management?
Share this post Share on facebook Share on google Share on twitter Share on linkedin Share on pinterest Share on print Share on email Bipolar…
Propranolol for TBI
PROPRANOLOL FOR TRAUMATIC BRAIN INJURY Traumatic brain injury can significantly impact an individual’s life, in terms of cognitive, behavioral, and physical impairments. Among these, aggression…
Top 5 Psychiatry Articles Discussed on PEF
Happy New Year to all PEF Followers I want to thank you all for following Psychiatry Education Forum and giving me the encouragement to continue…
Role of ANK3 in Bipolar Disorder
Share this post Share on facebook Share on google Share on twitter Share on linkedin Share on pinterest Share on print Share on email Ankyrin-3…
Asenapine: Transdermal vs Sublingual?
ASENAPINE: TRANSDERMAL VS SUBLINGUAL This post will summarize the key differences between the transdermal and sublingual formulation of asenapine in the following 10 minutes of…
Bipolar Disorder with comorbid ADHD
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Lithium & Renal Damage: Prevention?
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Role of NAC for Treatment-Resistant OCD
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Montelukast & Neuropsychiatric Adverse Events
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Comparing Serotonin Modulators: Trazodone vs Nefazodone
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Grief, Persistent Complex Bereavement Disorder Versus Prolonged Grief Disorder
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Remdesivir & Psychotropics Interactions
On Oct 22, 2020: FDA approved the antiviral medication Remdesivir for the treatment of COVID-19 requiring hospitalization. This was the first treatment for COVID-19 to…
Lithium Formulations & Dosages
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ALKS 3831 (Olanzapine/Samidorphan): Investigational Atypical Antipsychotic Drug
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Treatment-Resistant PTSD Nightmares Management
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Beware of “Benadryl Challenge” on TikTok: FDA Warning
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Why Patients with Dementia develop Behavioral Symptoms?
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FDA Update: Boxed Warning for Benzodiazepines
On Sep 23, 2020: FDA released this new announcement in their Drug Safety Communication, that the following update will be included in the Boxed Warning…
How do Antidepressants Cause Bruxism?
Bruxism is an involuntary activity of the jaw musculature characterized by jaw clenching, bracing, gnashing, and grinding of the teeth. Antidepressants induced bruxism is an…
How to Use Lithium During Pregnancy & Postpartum?
Lithium is considered a gold-standard mood stabilizer for the management of bipolar disorder. How about managing bipolar disorder with lithium during pregnancy OR for a…
PTSD Treatment if Prazosin fails: Doxazosin
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Evidence-Based Prevention Guidelines of Alzheimer’s Disease
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25% Price Drop: 1st CME Conference
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Comparing Antidepressants: Long-Acting Formulations
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Peer Reviewer for Psychiatry Education Forum
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Medications Induced Neutropenia: Avoid them with Clozapine.
Neutropenia is the single most important risk factor for infection and Clozapine is well known for the increased for neutropenia. This neutropenia risk will increase…
First FDA Approved Transdermal Antipsychotic: Asenapine (SECUADO®)
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Choosing Antidepressants Based on Comorbid Medical Conditions
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Cognitive Impairment with Traumatic Brain Injury
Traumatic brain injury can significantly impact an individual’s life, in terms of cognitive, behavioral and physical impairments. Among these, cognitive impairments are often the most…
Mood Stabilizers: Drug Interactions
This short 10 min video will discuss the important drug interactions for commonly used mood stabilizers for bipolar disorder management: Our course chapter will compare…
PEF Coffee Club: Bipolar Depression
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Snorting your way out? Using Stimulants for Depression
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Treatment-Resistant OCD: Can NAC Help?
A 36 year-old-female with history of Obsessive-Compulsive Disorder (OCD) is currently on fluvoxamine 300 mg/day with clomipramine 250 mg/day with persistence of intrusive obsessive thoughts…
Peer2Peer ChatRoom: Our New Course Feature
PEF Peer2Peer ChatRoom (PEF P2P) is a new feature for Physician’s Guide for Clinical Psychiatry subscribers. This ChatRoom brings together fellow psychiatric practitioners in our…
Grinding your Teeth in Depression
We all know about the risk of extrapyramidal symptoms with the use of antipsychotics. A similar risk can also be seen with antidepressants, but this…
Intranasal Olanzapine: New Drug-Device Product for Acute Agitation?
Agitation is seen in various psychiatric disorders including bipolar disorder and schizophrenia. The use of intramuscular and intravenous medications is common in hospital settings for…
Antidepressants & Restless Leg Syndrome (RLS)
Do you know of a condition “which causes such suffering that it should be known by every physician”?(1) That is what Ekbom, the neurologist who…
Neuroanatomy of Addiction
Understanding the neuroanatomy of the reward pathway and related circuitry is important in psychiatry, as abnormalities in these pathways are known to have a role…
‘Breaking Bad’ on a Routine Urine Drug Screen: The case of an innocent drug-positive
Post Contribution by Dr. Lena Palaniyappan Often we request urine drug screening when we suspect possible drug use, but cannot trust what the patient says.…
Clozapine and New-Onset Obsessions
Clozapine as a treatment option has many strengths. But it also has some weaknesses. This week I had a patient who has been stable on…
The Fire of Psychosis
Journalists write a lot more than psychiatrists, right? But how can you write meaningfully when your “brain is on fire”? A 24 year old New…
Atypical Psychosis: Discussion Series Announcement
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Psychotropic Dose Conversions: Email Lecture Series
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Duloxetine FDA Approved for Pediatric Fibromyalgia (age 13-17 yr)
FDA has expanded the duloxetine indication for the treatment of fibromyalgia in pediatric population (age 13-17 yr). Duloxetine is now approved for following disorders: Major…
Non-Psychiatric Medications with: Neuropsychiatric Adverse Events (Email Lecture Series)
Physician’s Guide for Clinical Psychiatry’s Next Triweekly Email Lecture Series Announcement: In this email lecture series, we will discuss the neuropsychiatric adverse events from following…
Neuroleptic Malignant Syndrome: Diagnostic Criteria
This post is dedicated to the discussion of diagnostic criteria for neuroleptic malignant syndrome. Here is the summary of an international consensus study of Neuroleptic…
Catatonia: Kahlbaum & Kraepelin
REFERENCES: Book: CATATONIA. From Psychopathology to Neurobiology. (HIGHLY RECOMMENDED) (amazon) Kahlbaum KL: Klinische Abhandlungen über psychische Krankheiten. 1. Heft: Die Katatonie oder das Spannungsirresein. Berlin,…
Burning Mouth Syndrome and Psychotropic Medications
Today we are excited to announce that we crossed 250 chapters in Physician’s Guide for Clinical Psychiatry Course. Here is Chapter #252 (which is available…
Clozapine, REMS and COVID-19
FDA issued the statement on March 22, 2020 regarding the patient access to REMS (Risk Evaluation and Mitigation Strategy) medications like clozapine during COVID-19 public…
Psychotropics Induced Sexual Dysfunction
Physician’s Guide for Clinical Psychiatry’s next lecture series will discuss the psychotropics sexual side effects in the following six chapters/emails: (1) WHAT QUESTIONS TO ASK? (MARCH…
Tobacco Use Disorder: Lecture Series
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Do SSRIs have Active Metabolite?
References: Fuller RW, Snoddy HD, Krushinski JH, Robertson DW. Comparison of norfluoxetine enantiomers as serotonin uptake inhibitors in vivo. Neuropharmacology. 1992 Oct;31(10):997-1000. (PubMed PMID: 1279447)…
Bipolar Depression Updated Guidelines: Psychopharmacology Algorithm Project
The Psychopharmacology Algorithm Project at the Harvard South Shore Program published algorithms for bipolar depression in 1999 and 2010. They just released their updated guidelines…
Depression & Hypothyroidism: 8 Clinical Facts
References: Minerva Endocrinol. 2013 Dec;38(4):365-77. (pubmed) J Affect Disord. 2014 Dec;169:112-7. (pubmed) Arch Intern Med. 2010 Dec 13;170(22):1996-2003. (pubmed) Psychoneuroendocrinology. 2015 Aug;58:114-9. (pubmed) Facebook Twitter…
Psychotherapy of Choice for PTSD?
FOR PHYSICIAN’S GUIDE FOR CLINICAL PSYCHIATRY SUBSCRIBERS: (Read Chapter 11.1): VA/DOD Clinical Practice Guidelines for PTSD and Acute Stress Disorder. This chapter will summarize these…
Hydroxyzine and QTc Prolongation
For Physician’s Guide for Clinical Psychiatry Subscribers: Read this chapter for details: (2.34) OTHERS: Hydroxyzine and QTc Prolongation. Read Course Chapter Dr. Harvinder Singh Admin,…
Antidepressants and Risk of Hyponatremia
For Physician’s Guide for Clinical Psychiatry Course Subscribers: (This chapter is only available to course subscribers) This topic will be discussed in the following sections:…
FDA Warning: Increased Cancer Risk with Lorcaserin
On 01-14-2020, FDA released this alert of possible association of cancer with Lorcaserin: FDA mentioned that at this time, the cause of the cancer is…
Dasotraline: New Norepinephrine-Dopamine Reuptake Inhibitor
Dasotraline is an investigational medication discovered by Sunovion Pharmaceuticals Inc. and is currently under development for the treatment of: ADHD (in children) and Binge eating…
Lithium Induced Neuropathy
Lithium induced neuropathy is a rare side effect of lithium. We will discuss this adverse event in the following sections: Underlying mechanism. Clinical Presentation: onset,…
Psychotropic Drug Interactions: Clozapine and GERD Medications.
Detailed answer is available in our first email of Psychotropics Drug-Drug Interactions lecture series:- <a data-elementor-open-lightbox=”” href=”https://app.getresponse.com/view/a62b/EwvVVzw/whArc/email-message/bhdkY” target=”_blank” rel=”noopener noreferrer”> <img width=”599″ height=”638″ src=”https://psychiatryeducationforum.com/project1/wp-content/uploads/2020/01/Screen-Shot-2020-01-08-at-1.20.08-PM.png” alt=””…
DAYVIGO™ (Lemborexant): FDA Approved for Insomnia.
On Dec 23, 2019 Eisai Inc. announced the FDA approval of DAYVIGO™ (Lemborexant) for insomnia management. This post will summarize the important clinically relevant facts…
Our Top 5 Posts & Lecture Series of 2019: Happy New Year
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Lumateperone (Caplyta): New Antipsychotic Approved for Schizophrenia
FDA has approved this new antipsychotic CAPLYTA (lumateperone) for the treatment of schizophrenia. This post will summarize the important clinically relevant facts regarding this medication,…
FDA Warning: Gabapentin and Serious Breathing Difficulties
FDA issued the following warning on 12/19/2019, and requires this information to be included in the package insert of this medication class: Combination of Gabapentinoids…
Prescribing Psychotropics with Medical Co-Morbidities
Detailed answer is available in our next email in the lecture series: <h3><a href=”https://app.getresponse.com/view/a62b/EFlZJSI/whArc/broadcast/18Akc” target=”_blank” rel=”noopener noreferrer”>Antidepressants use with Cardiac Risk</a></h3> <img width=”980″ height=”735″ src=”https://psychiatryeducationforum.com/project1/wp-content/uploads/2019/12/Antidepressants-Cardiac.001.jpeg”…
MDD: Switch vs Augmentation?
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Mood Stabilizer Comparison: CANMAT & ISBD (2018)
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Restarting Clozapine After Missed Dose
Answer: <img width=”1024″ height=”729″ src=”https://psychiatryeducationforum.com/project1/wp-content/uploads/2019/10/Screen-Shot-2019-10-29-at-3.32.28-PM-1024×729.png” alt=”” srcset=”https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2019/10/Screen-Shot-2019-10-29-at-3.32.28-PM.png?resize=1024%2C729&ssl=1 1024w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2019/10/Screen-Shot-2019-10-29-at-3.32.28-PM.png?resize=300%2C213&ssl=1 300w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2019/10/Screen-Shot-2019-10-29-at-3.32.28-PM.png?resize=768%2C546&ssl=1 768w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2019/10/Screen-Shot-2019-10-29-at-3.32.28-PM.png?w=1196&ssl=1 1196w” sizes=”(max-width: 1024px) 100vw, 1024px” /> <h3>Detailed answer is available at following…
Long-Acting Antipsychotics Dose Conversion.
Dr. Harvinder Singh, MD Admin, Psychiatry Education Forum Facebook Twitter Instagram Youtube Linkedin Physician’s Guide for Clinical Psychiatry Course Subscribers will have more detailed access…
Autism Spectrum Disorder: Pharmacological Management
Autism spectrum disorder is a neuro-developmental disorder characterized by deficits in social communication and social reciprocity, as well as repetitive behavior and restricted interests. First…
Antidepressants Induced Sexual Dysfunction
(Q) 28 year old male with history of major depressive disorder, reports having sexual side effects on trial of fluoxetine, sertraline, mirtazapine and venlafaxine.…
Antidepressants: Mechanism of Action (Part-2)
(Q.1): Which of the following antidepressant medication acts via: 5HT-2 Antagonism 5HT-3 Antagonism Alpha 2 Antagonism Venlafaxine Mirtazapine Vortioxetine Vilazodone (Q.2):…
Antidepressants: Mechanism of Action (Part-1)
(Q.1): Which of the following antidepressant medication acts via: 5HT-2 Antagonism 5HT-3 Antagonism Alpha 2 Antagonism Venlafaxine Mirtazapine Vortioxetine Vilazodone (Q.2): Which…
Duration of Antipsychotic use after Mania Remission.
Before proceeding further: Submit your answer first ANSWER: (c) 6 MONTHS (a) Continuing antipsychotics beyond 6 months (24 weeks) may not further protect against mania recurrence…
Naltrexone XR (Vivitrol)
This podcast will be summarized in the following sections: (1) Assessment: before initiation of Naltrexone XR (2) Clinical Opiate Withdrawal Scale (COWS) (3) Naltrexone (oral)…
Triweekly Email Summary Published (Sep 2019)
Click here for more details: https://course-email-summary.subscribemenow.com/ Free preview of our email sent today: Bipolar Disorder Guidelines: Mania (CANMAT & ISBD): http://bit.ly/Email-Summary-Bipolar-1
Join our Email Newsletter
Dear Psychiatry Education Forum Members. We send 1-2 educational emails/week to our email subscribers. We have upgraded to a new email service provider and this…
Lead Poisoning in Children
This post will be summarized by answering the following questions: (Q.1): What are the Neurological and Non-Neurological Symptoms of Lead Poisoning? (Q.2): What are the…
Excoriation (Skin-Picking) Disorder Management
Management of Excoriation (Skin-Picking) disorder will be discussed in the following two chapters (video podcasts). This brings our total course chapters count to 225. In…
Physician’s Guide for Clinical Psychiatry: 6 Months Anniversary Announcements.
Physician’s Guide for Clinical Psychiatry course was released 6 months ago on Jan 19 with 180 chapters. We just published our 222nd chapter yesterday (= 42 chapters…
Suicide Risk Evaluation
Suicide risk assessment is the most important aspect of psychiatric evaluation. This video podcast will discuss the clinical factors that may increase or decrease the…
Top 3 Most Viewed Posts Last Week
Before this summary, I want to thank you all for subscribing to our YouTube channel (Psychiatry Education Forum): we crossed 100 subscribers this week 🙂…
Mental Status Exam: Back to Basics
Hello Friends. This post is dedicated to our new PGY1 psychiatry residents. This video podcast will summarize the basic details of a mental status examination. Highly recommended…
Psychiatry and Medical Co-Morbidities: Thrombocytopenia
Answer is available in our next video podcast here: Detailed answer available for course subscribers here: https://mailchi.mp/ac53f9c8e8fb/antidepressants-and-risk-of-thrombocytopenia
Psychiatry Education Forum Updates (June 2019)
Hello Friends. June is almost over and so is half of 2019 🙂 How are you all liking our posts so far? Please do not…
Antidepressant with Medical Co-Morbidities
Post your answers below We have summarized this topic in this short 20 min video podcast here: https://youtu.be/UXYBXOjUNuI
Q: Bipolar disorder, Depression
Post your answer by using “Leave a Comment” option below. More detailed answer is available here: https://mailchi.mp/62acf1868385/comparing-fda-approved-medications-bipolar-1-depressed
Drug Interactions: HIV Medications and Psychotropics.
Answer posted here: https://mailchi.mp/2c27d4fc37d1/drug-interaction-hiv-medication-psychotropics
Cariprazine (Vraylar) Approved for Depressive Episodes in Bipolar I Disorder
Cariprazine (Vraylar) was initially approved for acute treatment of manic or mixed episodes associated with bipolar I disorder in adults. This week FDA also approved…
Antipsychotics and Warfarin Interactions
Answer Posted: https://psychiatryeducationforum.teachable.com/courses/451404/lectures/10380068 Subscribe for similar clinically relevant topics and podcasts.
Comparing Antidepressants: (1) SSRIs vs SSRIs.
Chapter: http://bit.ly/Comparing_Antidepressants_1 YouTube: https://youtu.be/lB3l77VA4bc Chapter: http://bit.ly/Comparing_Antidepressants_2 YouTube: https://youtu.be/u8WLCAcv4tE Subscribe for similar clinically relevant topics and podcasts.
Behavioral Symptoms Management in Dementia: Lecture Series.
Welcome to Behavioral Symptoms Management in Dementia Lecture Series. This post will summarize the list of chapters (based on their release dates). Here is our…
Antidepressants use with Renal Impairment.
Answer with detailed explanation is available in our following course chapter (available for free access): Subscribe for similar clinically relevant topics and podcasts.
Long Acting Antipsychotics Dose Conversions.
This table will summarize the dose conversion between: (1) Oral Risperidone (Risp) (2) Oral Paliperidone (Invg) (3) Risperidone Consta (R. Cont) (4) Invega Sustenna (I.…
Premenstrual Dysphoric Disorder (PMDD)
This is our fifth video podcast and will be summarized in the following sections: Diagnosing PMDD. PMS vs PMDD. Evaluating PMDD with Scales. Treatment Options:…
FDA Psychiatric Medication Shortages (April 2019)
Following Psychiatric medications are CURRENTLY IN SHORTAGE: (1) Buspirone (2) Diazepam Injection (3) Diphenhydramine Injection (4) Flurazepam Hydrochloride Capsules (5) Fluvoxamine ER Capsules (6) Haloperidol…
Video Podcast #1: Comparing Mood Stabilizers
This is our first video podcast lecture. This podcast will compare Lithium, Depakote, Carbamazepine, Oxcarbazepine and Lamotrigine in following sections: FDA Indications. CANMAT and ISBD…
FDA Approved Zulresso (brexanolone) for Post-partum Depression.
FDA approved Zulresso (brexanolone) injection for intravenous (IV) use for the treatment of postpartum depression (PPD) in adult women. Mechanism: Brexanolone is positive allosteric modulator…
Metformin for treatment of antipsychotic induced weight gain.
↓ ↓ Answer: 30 eGFR < 30 mL/min/1.73 m2: Metformin isContraindicated eGFR between 30-45 mL/min/1.73 m2 : Initiation of metformin is not recommended If eGFR falls…
Updated Guidelines by International Society of Psychiatric Genetics
International Society of Psychiatric Genetics (ISPG) updated their guidelines on the use of genetic testing in psychiatric practice. Here is a summary of these recommendations:…
Delirium Rating Scale-Revised-98 (DRS-R-98)
Delirium screening tools such as the Confusion Assessment Method and the Delirium Symptom Interview: are designed to detect some delirium symptoms but not to measure…
Esketamine (Spravato) FDA approved for Treatment Resistant Depression.
Esketamine is a glutamate receptor modulator: acts as noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. On March 05, 2019: FDA approved Spravato (esketamine) nasal spray, as an…
Autism spectrum disorder: co-morbid symptoms management
Autism spectrum disorder is a neurodevelopmental disorder characterized by deficits in social communication and social reciprocity, as well as repetitive behavior and restricted interests. ↓…
Antipsychotics Induced Edema.
Answer: C ↓ ↓ (190th Chapter Added to Course): Free preview available for next 48 hours only: Chapter #(2.8): Antipsychotics Induced Edema: Evaluation & Management.…
Warfarin and Antidepressants Drug Interactions
↓ ↓ Answer: Fluoxetine. Detailed Explanation Posted in Following Course Updated Chapter: (3.4) ANTIDEPRESSANTS and Warfarin (Chapter Updated) https://psychiatryeducationforum.teachable.com/courses/physicians-guide-for-clinical-psychiatry/lectures/8430865 Dr. Harvinder Singh, M.D. (Admin & Course…
(Q.3): Neuro-anatomical Correlates of Traumatic Brain Injury
Question Series on Traumatic Brain Injury Continues…. Read below for answer and other details: Symptom 1: Patient with impairments of consciousness following traumatic brain injury.…
Q: Optimal Duration of Augmentation Antipsychotic use in Bipolar Disorder?
Patient with diagnosis of bipolar I disorder had remission of his recent manic episode with combination of mood stabilizer (lithium/ divalproex) and antipsychotic (risperidone/ olanzapine)…
Somatic Symptom and Related Disorders (#2): Management of Medically Unexplained Symptoms in Primary Care.
Kroenke (1) published the following stepped approach for evaluation and management of medically unexplained symptoms in primary care setting: STEP #1: Determine Severity (a) for acutely…
Somatic Symptom and Related Disorders (#1): Differentiating Disorders.
DSM-5 Somatic Symptom & Related Disorders includes: Somatic Symptom Disorder Illness Anxiety Disorder Conversion Disorder (Functional Neurological Symptom Disorder) Psychological Factors Affecting Other Medical Conditions…
Catatonia (#3): Treatment with Benzodiazepines.
FIRST LINE MEDICATION: BENZODIAZEPINES (LORAZEPAM). Route of administration: IV or IM preferred over oral. Initiating dose of lorazepam: 2 mg (Lorazepam Challenge Test) Examine patient…
Catatonia (#2): Catatonic Disorder Due to Another Medical Condition: 293.89 (F06.1)
This post will focus on likely causes for catatonia secondary to underlying medical conditions. DSM-5 defines this as Catatonic Disorder Due to Another Medical Condition:…
Catatonia (#1): History of Catatonia: Kahlbaum & Kraepelin.
Kahlbaum is well known for his monograph “Catatonia or Tension Insanity“, where he described catatonic symptoms as having behavioral and motor components. He described this…
Atypical Antipsychotics Augmentation for Treatment-Resistant Depression.
A Systematic Review and Network Meta-Analysis conducted by Peng Xie et al. investigated the comparative efficacy and tolerability of adjunctive atypical antipsychotics for treatment-resistant depression.…
Dose Conversion: Risperidone Consta & Invega Sustenna
(Q.1): HOW TO CONVERT ORAL RISPERIDONE TO RISPERIDONE CONSTA? ORAL RISPERIDONE RISPERIDONE CONSTA 3 mg/day or less. 25 mg >3 to <5 mg/day or less…
Stimulant and Guanfacine combination for ADHD: (#3) Comorbid Oppositional Symptoms in ADHD.
The following study by Robert L. Findling et al tested the effect of guanfacine extended release (GXR) adjunctive to a psychostimulant on oppositional symptoms in…
Stimulant and Guanfacine combination for ADHD: (#2) Cognitive Effects.
The following study done by Dr. James T. McCracken et al tested the effects of stimulant and guanfacine monotherapies relative to combined treatment on cognitive functions important in ADHD.…
Stimulant and Guanfacine combination for ADHD: (#1) Cardiovascular Effects.
Q: Is this combination safe and well tolerated from cardiovascular side effect profile of individual medications? Stimulants are known for increase in pulse…
Lithium and Risk of Hypercalcemia & Hyperparathyroidism
This post will focus on: Differentiate Lithium associated hypercalcemia/hyperparathyroidism from primary hyperparathyroidism. Symptoms of hypercalcemia. Monitoring guideline. LITHIUM ASSOCIATED HYPER-CALCEMIA/ HYPER-PARATHYROIDISM PRIMARY HYPER-PARATHYROIDISM…
Opioid use disorder: Buprenorphine/Naloxone, Methadone & Naltrexone.
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