Can Depakote help with Delirium?

Delirium is one of the most commonly encountered psychiatric diagnosis in the hospital setting. Untreated delirium can have significant negative effects on patients’ morbidity and mortality. For this reason, understanding the treatment of delirium is clinically relevant for every medical practitioner. 

Delirium can present with hyperactive, hypoactive or mixed clinical presentations. Antipsychotics are commonly used for the treatment of delirium management but can depakote help with delirium?

Let’s begin by answering this question first:

When should Depakote be AVOIDED in delirium treatment?

Answer: Hypoactive Delirium

Here is one of the slides from our academy presentation on this topic:

ANNOUNCING ACADEMY’S NEXT VIDEO DISCUSSION RELEASE TODAY:

This chapter will be summarized in the following 9 sections/questions:

(1) Discussion of delirium subtypes.

(2) When will you USE depakote for delirium management?

(3) How to dose depakote in delirium: including in elderly patients.

(4) When to AVOID depakote during delirium?

(5) When to use depakote over antipsychotics for delirium management?

(6) Role of depakote in delirium management with specific medical co-morbidities.

(7) Comparing Depakote with Carbamazepine and Phenobarbital for alcohol withdrawal delirium management.

(8) What dose of depakote is found effective for corticosteroid-induced delirium?

(9) Comparing Depakote and Carbamazepine for patients with traumatic brain injury related delirium with agitation.

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