Can Cariprazine Help with Anxious Depression?

Patients with major depressive disorder (MDD) and prominent anxiety symptoms — often referred to as anxious depression — experience:

Poorer response to antidepressant monotherapy
Longer time to remission
Increased risk of suicidal ideation
Higher side effect burden and discontinuation rates

Adjunctive Cariprazine may provide dual benefits in treating Major Depressive Disorder (MDD) with comorbid anxiety — a clinical scenario often associated with treatment resistance and functional impairment.

Take a look at this slide from the Academy session—it explains how Cariprazine might work to alleviate symptoms of anxious depression

CARIPRAZINE: MECHANISM OF ACTION

FOR ACADEMY MEMBERS:

🧠 Clinical Implications of Anxious Depression
⚙ Cariprazine: What is the Mechanism of Action?
🧐 Journal Club: In-depth Review of the 2025 Phase 3 Study
📊 Understanding Anxiety Scales: HAM-D vs HAM-A
💊 What Dose of Cariprazine is Most Effective in Anxious vs Non-Anxious Depression?
💊 Is 3 mg Better than 1.5 mg?
⚠ Did Cariprazine Worsen Anxiety in Any Group?
🛑 Common Side Effects Observed
📚 How Cariprazine Compares to Other Atypical Antipsychotics (e.g., Brexpiprazole, Aripiprazole)
🎓 Key Clinical Takeaways

Can Cariprazine Help with Anxious Depression?

[FOR ACADEMY MEMBERS ONLY]

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