Antipsychotics Induced Nocturnal Enuresis

Nocturnal Enuresis, also known as bedwetting, is one of the underrecognized side effects from atypical antipsychotics. A comparative cohort study found that approximately one in five patients on clozapine reported nocturnal enuresis, and this was higher in comparison to risperidone, olanzapine and quetiapine. 

Medical professionals should include this in their evaluation as many patients may be embarrassed to disclose this side effect.

Let’s answer this question first:

Q: Which of the following neurotransmitter is known to cause blockade in the basal ganglia thereby causing involuntary enuresis?

Answer: Dopamine

Here is one slide from our academy’s presentation on this topic:

FOR ACADEMY MEMBERS:

Antipsychotics and Nocturnal Enuresis

This chapter will be summarized in the following sections:

  • Antipsychotics: which one to Avoid & which one are Preferred?
  • Neurotransmitters‘ action on Urinary Tract
  • Likely Mechanism behind this adverse event
  • How to Manage?

Antipsychotics & Nocturnal Enuresis

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