Antipsychotics & risk of Hypersexual or Paraphilic Behaviors
We know that dopamine agonism can result in hypersexual or paraphilic behaviors but interestingly, case reports for second-generation antipsychotics association with increase in hypersexual behavior is seen. Note that sexual dysfunction is more common than hypersexual side effects with antipsychotics.
This chapter will summarize this topic in the following sections:
- Antipsychotics with highest and lowest risk of this adverse event.
- Likely mechanism of action of each antipsychotic.
- Role of 5HT-1A, 2B, 7 and alpha receptor affinities.
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