Valproate Induced Tremors

Valproate is considered the first-line medication for bipolar disorder management but is known to cause various adverse events. Among these adverse events, tremors are one of the common neurological side effects induced by valproate, with an incidence of 6-64% seen in epilepsy studies.

For this reason, we should have the knowledge to identify and manage these tremors induced by tremors. Psychiatry Education Forum Academy has released the latest video discussion on the Mood Stabilizers Adverse-Events Management Series today:

Let’s Answer this clinically relevant question first:

Which of the following risk factor is LEAST likely to induce tremors with valproate (VPA) use?

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SUBMIT YOUR ANSWERS FIRST 🙂

Answer:

(c) Switching to Depakote ER Formulation.

Here is one of the slides from our video presentation on this topic, explaining the reasons why controlled-release valproate release formulations are preferred:

This academy chapter will summarize this topic in the following sections:

  1. Risk Factors: that can be modified to treat VPA tremors.
  2. Clinical Features of VPA Tremors.
  3. Medication Options for VPA Tremors.
  4. What is next if Propranolol Fails?

This discussion is a part of our mood-stabilizer adverse events section, with chapters on the management of following valproate adverse events management:

  1. Valproate & Thrombocytopenia
  2. Valproate & Hair Loss
  3. Valproate & High Ammonia
  4. Valproate & Tremors

Valproate Adverse Events Management

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