Cyproheptadine for PTSD Nightmares
The diagnosis of PTSD requires the endorsement of one of two symptoms from the symptom clusters of (1) reexperiencing, (2) avoidance, and (3) sense of current threat.
Nightmares related to PTSD are included in the reexperiencing cluster. This includes having upsetting dreams that replay part of the traumatic experience or are clearly related to the experience. Prazosin have show efficacy with PTSD nightmares but some patients may not be able to tolerate this medication due to hypotensive effect and related events. What are the available treatment options in this clincial scenario?
Psychiatry Education Forum Academy have a lecture series on this topic with five likely medication options and one of them is Cyproheptadine.
This chapter will be discussed in the following sections:
- Mechanism of Action
- How to Dose for PTSD nightmares?
- Comparing studies for PTSD nightmares.
- Adverse Events
- Cautions & Contraindications
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