The diagnosis of PTSD requires the endorsement of one of two symptoms from the symptom clusters of (1) reexperiencing, (2) avoidance, and (3) sense of current threat.
Nightmares related to PTSD are included in the reexperiencing cluster. This includes having upsetting dreams that replay part of the traumatic experience or are clearly related to the experience. Prazosin have show efficacy with PTSD nightmares but some patients may not be able to tolerate this medication due to hypotensive effect and related events. What are the available treatment options in this clincial scenario?