Antidepressant Induced Excessive Sweating

Antidepressant-induced excessive sweating (ADIES) is reported in more than 20% of patients taking antidepressants. For this reason, the knowledge on how to identify and manage these side effects is of clinical importance for your daily practice. 

Let’s Answer this clinically relevant question first:

Antidepressants are LEAST LIKELY to cause excessive sweating at which of the following body location?

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Answer:

This first clinical trial for ADIES treatment conducted by Dr. Rajnish Mago, found that ADIES is commonly see in the scalp (62%), face (95%), neck (48%), and chest (57%). 

Reference: Mago R, Thase ME, Rovner BW. Antidepressant-induced excessive sweating: clinical features and treatment with terazosin. Ann Clin Psychiatry. 2013 Aug;25(3):186-92. Epub 2013 May 1. (PMID: 23638448)

ADIES can not only affect a person emotionally (by causing embarrassment) but can also increase the risk of dehydration or electrolyte deficiency for at-risk patients.

How can you manage a patient with excessive sweating from antidepressants, especially those who are responding positively to the treatment? 

This is what our academy’s following chapter will focus on:

This chapter will summarize antidepressants-induced excessive sweating in the following sections:

  1. Common body locations for excessive sweating from antidepressants?
  2. Likely mechanism behind antidepressants causing excessive sweating?
  3. Management: six medication options.

Antidepressants Induced Excessive Sweating

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