What Features Differentiates Bipolar Depression from MDD?

Q: What Features Differentiate Bipolar Depression from MDD?

Bipolar depression is characterized by significantly higher rates of:

  1. Psychomotor retardation
  2. Difficulty thinking
  3. Early morning awakening, morning worsening
  4. Psychotic features

NOTE:- Psychomotor retardation is the most robust feature distinguishing Bipolar depression from MDD. Also noted is more relevance of psychomotor retardation to Bipolar 1 vs Bipolar 2 & MDD.

Source: Mitchell et al. The British Journal of Psychiatry (2011) 199, 303–309.

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  3. Bipolar Psychopharmacology.
  4. Bipolar 2 Disorder vs Bipolar 1.
  5. Bipolar Disorder with Comorbid ADHD.

Bipolar and Related Disorder

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