Treating Pediatric Mania: Which Medications Reduce Symptoms Most Effectively?

The treatment of acute mania in children and adolescents remains a challenging clinical decision, often requiring a balance between efficacy and tolerability. While both antipsychotics and mood stabilizers are commonly used, recent research published in the Journal of the American Academy of Child & Adolescent Psychiatry (August 2024) sheds light on their comparative effectiveness and safety.

Watch this short YouTube video summarizing one of the findings from our Academy chapter summarizing the main findings of this study.

Which Medications Reduced Manic Symptomatology in Pediatric Bipolar?

If you’re looking for an in-depth analysis of this study, check out our new Academy Chapter:

ANTIPSYCHOTICS VS MOOD STABILIZERS:
FOR ACUTE MANIA IN CHILDREN & ADOLESCENTS

In this chapter, Dr. Harvinder Singh will cover the following key sections to enhance your understanding:

(1) Early vs Late Onset Bipolar Disorder: What’s the difference?

(2) Treating Manic Symptoms:

  • Preferred treatments
  • Which ones to avoid
  • Comparing treatments as individual options and as a class

(3) Response with Manic Episode Treatment:

  • Best treatment options
  • Treatments to avoid
  • Comparative analysis

(4) Efficacy for Depressive Symptoms: Which treatments are effective?

(5) Improving Functionality: Which treatments work best?

(6) Lower Dropout Rates:

  • Due to inefficacy
  • For any reason
  • Due to adverse events

(7) Adverse Events Comparison:

  • Prolactin elevation
  • BMI & weight changes
  • Cholesterol, triglycerides, glucose changes
  • Appetite increase, nausea, sedation
  • Extrapyramidal symptoms (EPS)

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