MDD Augmentation: L-MethylFolate

We continue our lecture series “10 Augmentation Strategies for MDD” with our fourth lecture on the role of L-MethylFolate as an augmentation for major depressive disorder (MDD).

L-MethylFolate [Deplin] is a prescription medical food approved by FDA and is indicated as an adjunctive treatment for MDD. L-MethylFolate is different from folic acid as this is biologically active form of folate & more readily crosses the blood-brain barrier.

Let’s answer this question first:

Which of the following high risk population with MDD will benefit from L-Methylfolate augmentation?

Here is one slide from this presentation answering this question:

The role of L-MethylFolate for MDD augmentation will be discussed in the following sections:

CHAPTER 4: L-METHYLFOLATE FOR MDD AUGMENTATION

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MAJOR DEPRESSIVE DISORDER:
10 AUGMENTATION STRATEGIES

Major Depressive Disorder: 10 Augmentation Strategies

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