L-Methylfolate for Depression: When to use?

L-MethylFolate is used as an augmentation agent to antidepressants in patients with major depression disorder, but who is a good candidate for considering L-Methylfolate as an augmentation agent?

One of the factor is patient taking medication interfering with conversion of folate to l-methylfolate, thereby affecting the synthesis of monoamines like serotonin. Here is the list of these medications:

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L-METHYLFOLATE FOR TREATMENT RESISTANT DEPRESSION

MTHFR & L-METHYLFOLATE

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