Augmentation Strategies for Clozapine-Resistant Schizophrenia?
Clozapine is considered a gold-standard medication for treatment-resistant schizophrenia, but close to 50% of these patients on clozapine may show poor or no response. What…
Clozapine is considered a gold-standard medication for treatment-resistant schizophrenia, but close to 50% of these patients on clozapine may show poor or no response. What…
Neutropenia is the single most important risk factor for infection and Clozapine is well known for the increased for neutropenia. This neutropenia risk will increase…
Clozapine as a treatment option has many strengths. But it also has some weaknesses. This week I had a patient who has been stable on…
Choose your answer first before scrolling down…. <strong>Answer: CYP1A2 interaction</strong></p><ul><li>Clozapine is extensively metabolized in the liver via the cytochrome P450 system. </li><li><strong>Cytochrome P450 isoenzyme 1A2…
FDA issued the statement on March 22, 2020 regarding the patient access to REMS (Risk Evaluation and Mitigation Strategy) medications like clozapine during COVID-19 public…
Detailed answer is available in our first email of Psychotropics Drug-Drug Interactions lecture series:- <a data-elementor-open-lightbox=”” href=”https://app.getresponse.com/view/a62b/EwvVVzw/whArc/email-message/bhdkY” target=”_blank” rel=”noopener noreferrer”> <img width=”599″ height=”638″ src=”https://psychiatryeducationforum.com/project1/wp-content/uploads/2020/01/Screen-Shot-2020-01-08-at-1.20.08-PM.png” alt=””…
Answer: <img width=”1024″ height=”729″ src=”https://psychiatryeducationforum.com/project1/wp-content/uploads/2019/10/Screen-Shot-2019-10-29-at-3.32.28-PM-1024×729.png” alt=”” srcset=”https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2019/10/Screen-Shot-2019-10-29-at-3.32.28-PM.png?resize=1024%2C729&ssl=1 1024w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2019/10/Screen-Shot-2019-10-29-at-3.32.28-PM.png?resize=300%2C213&ssl=1 300w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2019/10/Screen-Shot-2019-10-29-at-3.32.28-PM.png?resize=768%2C546&ssl=1 768w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2019/10/Screen-Shot-2019-10-29-at-3.32.28-PM.png?w=1196&ssl=1 1196w” sizes=”(max-width: 1024px) 100vw, 1024px” /> <h3>Detailed answer is available at following…
This podcast will summarize Clozapine-Induced Gastrointestinal Hypomotility (CIGH) in the following six sections:1. How clozapine can cause CIGH?2. Clinical signs of ileus states.3. Risk factors for CIGH…
#1: Make sure that blood clozapine levels are in the therapeutic range and the patient is taking the maximum tolerable doses of clozapine over at least 18-24…
Clozapine: Managing Side Effects By Dr. Harvinder Singh. Physicians are aware of serious side effects from clozapine including agranulocytosis, myocarditis, cardiomyopathy, pulmonary embolism and seizure…
Patient with treatment resistant schizophrenia is admitted for fifth time this year secondary to worsening of psychotic symptoms. He is compliant with medications and have…
40 year old patient with history of schizophrenia stabilized on clozapine presented with recent worsening of psychotic symptoms. He recently started smoking and initiated treatment…
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