Omega-3 Fatty Acids for MDD?
Recently Omega-3 polyunsaturated fatty acids, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) have drawn the clinical attention for the treatment of major depressive disorder. The…
Tag: Depression
Omega-3 Fatty Acids for MDD Treatment: Practice Guidelines
Detailed Answer is available in our first Journal Club discussion: Journal Club #1: ISNPR Practice Guidelines for Omega-3 Fatty Acids in the Treatment of Major…
How Long to Continue Antidepressants for MDD Treatment?
Once you have initiated antidepressants for MDD (Major Depressive Disorder) treatment and patient has achieved remission, how long will you continue this current antidepressant for?…
MDD Augmentation Strategies: Modafinil
Partial response, no response, or residual symptoms following antidepressant therapy is common in clinical psychiatry. Hence, it is of clinical importance to have knowledge of…
Comparing Antidepressants: Long-Acting Formulations
This post will focus on the following three available long-acting formulations of antidepressants: (1) FLUOXETINE CR: Comparing daily fluoxetine with weekly fluoxetine in terms of:…
ADHD & Depression: Psychotropic Drug-Drug Interactions
This question is more directed toward drug-drug interactions and the role of Cytochrome P450: Atomoxetine is metabolized by CYP2D6, so we should avoid medications inhibiting…
Choosing Antidepressants Based on Comorbid Medical Conditions
Let’s begin this discussion with the following hypothetical case: <img width=”640″ height=”360″ src=”https://psychiatryeducationforum.com/project1/wp-content/uploads/2020/08/Pink-Blooming-Bridal-Bouquets-Sales-Presentation-2-1024×576.png” alt=”” srcset=”https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2020/08/Pink-Blooming-Bridal-Bouquets-Sales-Presentation-2.png?resize=1024%2C576&ssl=1 1024w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2020/08/Pink-Blooming-Bridal-Bouquets-Sales-Presentation-2.png?resize=300%2C169&ssl=1 300w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2020/08/Pink-Blooming-Bridal-Bouquets-Sales-Presentation-2.png?resize=768%2C432&ssl=1 768w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2020/08/Pink-Blooming-Bridal-Bouquets-Sales-Presentation-2.png?resize=1536%2C864&ssl=1 1536w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2020/08/Pink-Blooming-Bridal-Bouquets-Sales-Presentation-2.png?w=1920&ssl=1 1920w, https://i0.wp.com/www.psychiatryeducationforum.com/wp-content/uploads/2020/08/Pink-Blooming-Bridal-Bouquets-Sales-Presentation-2.png?w=1280&ssl=1…
Journal Club #9: Is Ketamine Safe with History of Psychosis?
Journal Club #9: Is Ketamine Safe with History of Psychosis & Implications for Its Therapeutic Use. Article: JAMA Network Open. 2020 May; 3(5): e204693. In…
Depression and Glaucoma: The pain of pressure
What is the link between glaucoma and depression? There is a circular link. Patients with glaucoma have higher risk of becoming depressed, and being exposed…
Snorting your way out? Using Stimulants for Depression
Stimulants have been intuitively considered as treatment options for depression for a very long time. It is often said that Freud treated his own depression…
Bipolar Depression Updated Guidelines: Psychopharmacology Algorithm Project
The Psychopharmacology Algorithm Project at the Harvard South Shore Program published algorithms for bipolar depression in 1999 and 2010. They just released their updated guidelines…
Anti-Inflammatory Treatment: Effect on Depression and Adverse Effects.
JAMA psychiatry published this systematic review and meta-analysis of randomized clinical trials done by Ole Kohler and colleagues in 2014. According to author, this…
Brain Structure and Function Abnormalities in Major Depression Disorder
Brain Structure and Function Abnormalities in Major Depression Disorder (1) Reduced Functioning of Preforntal Cortex (primarily dorsolateral prefrontal cortex and striatum). The knowledge gained from…
Role of Endogenous Opioids in Depression
Role of Endogenous Opioids in Depression The roles of opioid receptors in pain and addiction is well known, but their function in mood…
Association of Hormonal Contraception With Depression
Association of Hormonal Contraception With Depression JAMA Psychiatry published this nationwide prospective cohort study online on September 28, 2016. Study Design: All…
NeuroAnatomical Location of Depression Symptoms
NeuroAnatomical Location of Depression Symptoms Amygdala and Prefrontal cortex: Guilt, Suicidality and Worthlessness. Nucleus accumbens: Pleasure, Interest, and Energy. Hypothalamus: Sleep and Appetite. Functional…