Antidepressants & Hyponatremia Risk
Clinical Case Discussion: Hyponatremia Risk with Antidepressants
Dr. Satinderpal Kaur (Family Medicine) & Dr. Harvinder Singh (Psychiatry) will continue their discussion to integrate clinical cases from Psychiatry and Medicine.
Our 7th clinical case discussion will focus on:
(1) Hyponatremia: Definition & Severity
(2) Symptoms of Hyponatremia: Mild & Severe
(3) Initial Assessment of Hyponatremia
(4) Understanding Laboratory Evaluation of Hyponatremia
(5) Understanding SIADH.
(6) Important Differential Diagnosis.
(7) Medications as cause for SIADH.
(8 Antidepressants & Hyponatremia: Likely Mechanism.
(9) Antidepressants & Hyponatremia: Risk Factors
(10) Antidepressants & Hyponatremia: High Risk Medications.
(11) Antidepressants & Hyponatremia: Moderate Risk Medications.
(12) Antidepressants & Hyponatremia: Lowest Risk Medications.
(13) Clinical Case Discussion
(2) Symptoms of Hyponatremia: Mild & Severe
(3) Initial Assessment of Hyponatremia
(4) Understanding Laboratory Evaluation of Hyponatremia
(5) Understanding SIADH.
(6) Important Differential Diagnosis.
(7) Medications as cause for SIADH.
(8 Antidepressants & Hyponatremia: Likely Mechanism.
(9) Antidepressants & Hyponatremia: Risk Factors
(10) Antidepressants & Hyponatremia: High Risk Medications.
(11) Antidepressants & Hyponatremia: Moderate Risk Medications.
(12) Antidepressants & Hyponatremia: Lowest Risk Medications.
(13) Clinical Case Discussion
LET’S BEGIN BY ANSWERING THIS QUESTION:
Here is one slide from this clinical case discussion, answering this question:
According to this most recent meta-analysis published in European Psychiatry: the highest event rates were found for SNRIs (7.44%) followed by SSRIs (5.59%), and TCAs (2.66%). Mirtazapine is the preferred antidepressant.
(Reference: European Psychiatry. 2024;67(1):e20.)
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