Which Antiepileptics are Preferred in Pregnancy?
					When managing epilepsy in pregnant individuals, the choice of antiepileptic drugs (AEDs) plays a critical role in optimizing maternal and fetal outcomes. A recent study published in The Journal of Clinical Psychiatry reviewed the association between various AEDs and the risk of major congenital malformations.
The study found that
- Lamotrigine and Levetiracetam were associated with a lower risk of congenital malformations, making them preferred options for women of childbearing age and those who are pregnant.
 - In contrast, Valproate showed a significantly higher risk of major congenital malformations, reinforcing the recommendation to avoid its use during pregnancy when possible.
 
WATCH SHORT VIDEO SUMMARY:
The above video is from our Academy’s monthly summary of recently published, clinically relevant articles.
This month session summarized the following topics:
(A) WOMEN’S MENTAL HEALTH:
- Is Ketamine Safe in Pregnancy?
 - Which Antiepileptics are Preferred in Pregnancy?
 
(B) MDD + PTSD:
- Can Prazosin Augmentation help in patient with MDD with history of Trauma ?
 
(C) PSYCHOPHARMACOLOGY ADVERSE EVENTS:
- Can Zuranolone Impact Next-Day Driving, when used for Post-Partum Depression?
 
(D) PSILOCYBIN VS ANTIDEPRESSANTS:
- Which one is better for Moderate to Severe MDD: Psilocybin or Antidepressants
 
(E) INSOMNIA & RELATED DISORDERS:
- Lemborexant Safety with Comorbid Moderate to Severe COPD
 
(F) SCHIZOPHRENIA PSYCHOPHARMACOLOGY:
- Comparing Antipsychotics & Pneumonia Risk: Which one to Avoid?
 
(G) VAPPING CESSATION:
- New Potential Medication for Vaping Cessation.
 
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