Managing Psychopharmacology Adverse Events

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A Rapid-Decision Series

Managing Psychopharmacology Adverse Events

Point-of-care guidance for the adverse effects of psychiatric medications. Every chapter opens with what to do now, what not to do, and when to send the patient to the emergency department.

At the bedside · from Chapter 1
Suspected lithium toxicity: the next ten minutes
Do now
  • Hold the next lithium dose. Do not wait to see the patient first.
  • Triage red, amber or green on the patient, whatever the level says.
Do not
  • Advise drinking large volumes of water to “flush out” lithium.
  • Act on a single level without the time of the last dose and the time of the draw.
Emergency department now Same-day assessment Outpatient, with a safety net

Start from the problem in front of you

The questions clinicians bring most often, one click from the chapter that answers them.

Rapid Decision Series 3 · Sections 1–4 live

Managing Mood Stabilizer Adverse Events

Lithium, valproate, lamotrigine, carbamazepine and oxcarbazepine. Six sections, one every few days.

Read Table of Contents here
Rapid Decision Series 1
Complete · 21 chapters

Antipsychotics

Movement Disorders · Ch 1–5
Acute dystonia, akathisia, drug-induced parkinsonism, tardive dyskinesia and NMS.
Metabolic & Endocrine · Ch 6–10
Weight gain and metabolic syndrome, new-onset diabetes, dyslipidemia and hyperprolactinemia.
Cardiac & Autonomic · Ch 11–12
QTc prolongation and orthostatic hypotension.
The Clozapine Set · Ch 13–17
Agranulocytosis, myocarditis, constipation and ileus, sialorrhea and seizures.
Other Systemic & Quick Reference · Ch 18–21
Sedation, sexual dysfunction, edema and the quick-reference grid.
View Rapid Decision Series 1
Rapid Decision Series 2
Complete · 31 chapters

Antidepressants

Serotonergic & Neuropsychiatric · Ch 1–7
Serotonin syndrome, activation, akathisia, the bipolar switch, tremor, bruxism and the EPS cluster.
GI, Sleep & Affect · Ch 8–11
Nausea, insomnia and vivid dreams, sedation, and emotional blunting.
Metabolic, Sexual & Long-Term · Ch 12–14
Weight gain, sexual dysfunction and PSSD, and fracture risk.
Cardiac, Autonomic & Bleeding · Ch 15–20
QTc and conduction, SNRI hypertension, orthostasis, sweating, urinary retention and bleeding risk.
Laboratory, Stopping & Switching · Ch 21–24
Hyponatremia, DILI, hyperbolic tapering and cross-taper safety.
Agent-Specific Sets · Ch 25–29
Bupropion, mirtazapine, the serotonin modulators, TCAs and MAOIs.
Uncommon & Quick Reference · Ch 30–31
The rare events worth recognising, and the matrix that maps every adverse effect to every commonly prescribed agent.
View Rapid Decision Series 2
Rapid Decision Series 3
Sections 1–4 live · releasing to Oct 31

Mood Stabilizers

Lithium: Acute Toxicity & Level Problems · Ch 1–3
Lithium toxicity and when to send to the ED (Chapter 1, free), unexpected levels and sick-day rules, and neurologic symptoms including encephalopathy, serotonin syndrome and NMS.
Live
Lithium: Long-Term Organ Effects · Ch 4–7
Polyuria and nephrogenic diabetes insipidus, declining kidney function (Chapter 5, free), thyroid, calcium and parathyroid effects, and tremor, cognition, weight and skin.
Live
Lamotrigine · Ch 12–14
Live
Carbamazepine & Oxcarbazepine · Ch 15–18
Serious rash and HLA testing, hyponatremia, blood and liver toxicity, and drug interactions and autoinduction.
Tue, Oct 27
Across All Mood Stabilizers · Ch 19–21
Cardiac conduction, stopping safely, and the quick-reference monitoring and management grid.
Sat, Oct 31
View Rapid Decision Series 3

Inside every chapter

Bedside panel first

Do now, do not, five questions to ask, and a triage path: emergency department, same day, or plan.

The detail below

The reasoning, tables and figures for when you have time, with every source cited.

Copy-paste EMR note

A structured note for the decision you just made, ready to edit into the chart.

What to tell the patient

A plain-language counselling script for the conversation that follows.

Full access with an Academy membership

Every course in this series, plus the rest of the Academy library, for prescribers who need the answer during the visit, not after it.

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