How to Dose Varenicline for Smoking Cessation: A Comprehensive Guide

Smoking cessation is a critical step toward improving overall health, and varenicline has emerged as a highly effective aid in this journey. This blog post provides a detailed guide on dosing varenicline to help individuals quit smoking.

According to this article (Expert Opin Drug Discov. 2018;13(7):671-683), people who try to quit nicotine smoking:

  • 80% return to smoking within the first month
  • < 20% quit for six months
  • Only 3% remain abstinent for more than one year

Varenicline is one of the effective treatment for smoking cessation. Hence, it is important to have the knowledge on how to initiate treatment, and how is Varenicline compared to other available treatment options.

VARENICLINE: HOW TO DOSE?

  • First set a date to quit smoking.
  • Initiate Varenicline one week before this quit date. 
  • Take Varenicline after a meal and with a full glass of water. 
  • Begin with a dose of 0.5 mg/day for the first 3 days.
  • For the next 4 days: 0.5 mg twice daily (in the morning and in the evening). 
  • After the first 7 days: increase the dose to 1 mg twice daily (in the morning and in the evening).
  • Total duration of treatment: 12 weeks.
  • An additional 12 weeks of treatment is recommended for successful quitters to increase likelihood of long-term abstinence

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ADDICTION PSYCHIATRY:
SUBSTANCE USE DISORDER

DR. HARVINDER SINGH

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