VA/DOD Clinical Practice Guidelines for PTSD.

VA/DOD recently published clinical practice guideline for management of PTSD and acute stress disorder. 
According to these guidelines, monotherapy with which of the following medication is recommended in patients who choose not to engage in or are unable to access trauma focused psychotherapy

 


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According to VA/DOD recently published guidelines (June 2017): 

 

For Primary Treatment of PTSD: Individual Manualized Trauma Focused Psychotherapy is recommended over pharmacologic and non pharmacologic intervention.

 

Pharmacotherapy is only indicated for patient:

  • who choose not to engage in psychotherapy, or

  • who are unable to access trauma focused psychotherapy.

 

 

EVIDENCE

MODERATE

LOW

VERY LOW

RECOMMEND FOR

Fluoxetine

Paroxetine

Sertraline

Venlafaxine

   

SUGGEST FOR

 

Nefazodone

Phenelzine

Imipramine

SUGGEST AGAINST

Prazosin

 

Citalopram

Amitriptyline

Quetiapine

Olanzapine

Lamotrigine

Topiramate

RECOMMEND AGAINST

 

Divalproex

Tigabine

Guanfacine

Benzodiazepines

Risperidone

Ketamine

Hydrocortisone

D-Cycloserine

Note: for Prazosin indication for treatment of PTSD associated nightmares: No Recommendation For or Against. 

 


Source: VA/DoD Clinical Practice Guideline for the Management of Posttraumatic Stress Disorder and Acute Stress Disorder. Version 3.0 – 2017

 

Please do post your questions or comments below. 


Dr. Harvinder Singh, M.D. (Admin)


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