Typical Antipsychotics- Quiz Series.

Q.1: Typical Antipsychotics can be be safely used in which of the following patient population?

Q.2: Patient was started on typical antipsychotics and pt presented with severe orthostatic hypotension. Which of the following medication is contraindicated in the management of typical antipsychotics induced orthostatic hypotension?

Q.3: Which of the following typical antipsychotic is considered safe in overdose (compared to other atypical antipsychotics)?

Q.4: Patient presented to ED with complaints of drowsiness, mydriasis, rigidity, restlessness, decreased DTR (deep tendon reflexes), tachycardia, & hypotension. Pt reports overdosing on unknown amount of typical antipsychotic medication pills.
Which of the following management is not effective in patient with overdose on typical antipsychotics?

Q.5: Which of the following are NOT a contraindication for typical antipsychotics use?








Answer 1: (e) None of the above.

Typical Antipsychotics should be avoided in above mentioned conditions.

Patient presented to ED with shakes, body ache, hallucination and history of drinking unknown amount of alcohol: This patient is in alcohol withdrawal, and use of typical antipsychotics will increase the risk of seizure.

Patient presented to ED with Phencyclidine (PCP) intoxication: additive anticholinergic effects of PCP and typicalantipsychotics. Benzodiazepines should be used.

Patients with rigid form of Huntington’s disease: Pt may experience acute EPS.

Answer 2: (b) Epinephrine

Hypotension is produced by alpha adrenergic blockage property of typical antipsychotics, & these drugs also block the alpha adrenergic stimulating property of epinephrine, leaving beta adrenergic stimulating property untouched. As a result epinephrine will cause paradoxical worsening of hypotension and hence epinephrine is contraindicated in antipsychotic induced hypotension.

Answer 3: (b) Haloperidol

Answer 4: (c) Anti-emetics
Antiemetic action of typical antipsychotics limits the efficacy.

Answer 5: (e) All of the above are contraindications.


Please do post your questions or comments below. 

Dr. Harvinder Singh, M.D. (Admin)

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