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Answer 1: (e) None of the above.
Typical Antipsychotics should be avoided in above mentioned conditions.
Patient presented to ED with shakes, body ache, hallucination and history of drinking unknown amount of alcohol: This patient is in alcohol withdrawal, and use of typical antipsychotics will increase the risk of seizure.
Patient presented to ED with Phencyclidine (PCP) intoxication: additive anticholinergic effects of PCP and typicalantipsychotics. Benzodiazepines should be used.
Patients with rigid form of Huntington’s disease: Pt may experience acute EPS.
Answer 2: (b) Epinephrine
Hypotension is produced by alpha adrenergic blockage property of typical antipsychotics, & these drugs also block the alpha adrenergic stimulating property of epinephrine, leaving beta adrenergic stimulating property untouched. As a result epinephrine will cause paradoxical worsening of hypotension and hence epinephrine is contraindicated in antipsychotic induced hypotension.
Answer 3: (b) Haloperidol
Answer 4: (c) Anti-emetics
Antiemetic action of typical antipsychotics limits the efficacy.
Answer 5: (e) All of the above are contraindications.
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Dr. Harvinder Singh, M.D. (Admin)
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