Clozapine missed dose Q: 38-year-old patient with history of treatment-resistant schizophrenia was stable on clozapine 350 mg bedtime dosing. He stopped his clozapine four days ago and is admitted to the inpatient psychiatry unit for worsening psychotic symptoms. How will you initiate his clozapine on the first day of hospitalization? Restart clozapine at 350 mg bedtime dose without need for titration Restart clozapine at 250 mg bedtime with daily increase of 50 mg/day. Restart clozapine at 150 mg bedtime with daily increase of 50 mg/day. Restart clozapine at 12.5 mg twice daily with daily increase of 50 mg/day Time's up Share
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