Clozapine Interactions-2

Q: A 23-year-old man was admitted to the inpatient psychiatry unit after a suicide attempt 3 weeks ago. This was his second suicide attempt this year. He has a 2-year history of schizophrenia and has been tried on 3 different antipsychotic agents with breakthrough symptoms. While on the ward, he is pleasant and cooperative with, though continues to hear voices which instruct him to kill himself. The patient is a creative writer and has been coping with these voices by immersing himself in his work. He spends all day on his laptop writing and will have 8-10 cups of coffee daily to fuel his writing streak.
You would like to start the patient on clozapine but need to mindful of which of the following?


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