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  • Dr. Harvinder Singh

    April 23, 2021 at 2:14 am

    Here is what I will recommend but let’s hear others’ recommendations as well.

    I will motivate the patient to not drink with lithium as the risk is high. If the patient is still drinking: aim for low alcohol (no specific amount is listed in literature) and maintain their hydration. If the patient has a history of alcohol use disorder or other addiction behaviors: I will not recommend even a low amount as the risk of them drinking more is high.

    Here is the summary of lithium & alcohol interaction:

    • Acute alcohol does not affect lithium absorption, elimination, distribution, or clearance, but alcohol can increase serum lithium concentrations when taken with alcohol. (1)
    • Another concern is increased alcohol use induced diuresis by antagonizing ADH, which can indirectly place a patient at risk of high lithium levels.


    1. Clin Pharmacol Ther. 1985 Jul;38(1):52-5.