Designer Drugs: Clinical Features

24 year old male is brought to the hospital emergency room by police officer for aggressive behaviors and worsening paranoia. Patient reports using excessive amounts of unknown designer drugs. 

Vitals: Heart rate: 134, BP: 162/98; Temp: 102 F.

On Exam: Patient is diaphoretic with evident muscle spasms. Dentition is poor with perforated nasal septum. No conjunctival injections noted. 
Lab work revealed rhabdomyolysis. 

Which of the following designer drug is likely responsible for this presentation?

 


BEFORE SCROLLING DOWN ==>

SUBMIT YOUR ANSWERS FIRST 🙂

.

.

.

.


Designer drugs are synthetic analogs of controlled substances. This post will focus and compare various clinical features for following three classes of designer drugs:

  1. Synthetic Stimulants: Bath Salts, Sextacy, M-Cat etc.

  2. Synthetic Cannabinoids: Spice, K2, K9 etc.

  3. Synthetic Hallucinogens: N-bomb, Solaris, Smiles etc.

 


 

CLINICAL FEATURES

SYNTHETIC

STIMULANTS

SYNTHETIC 

CANNABINOIDS

SYNTHETIC

HALLUCINOGENS

 

VITALS

Hyperthermia

+

 

+

Tachycardia

+

+

+

Hypertension

+

+

+

 

PHYSICAL EXAM

Conjunctival Injection
 

+

 
Epistaxis

+

 

+

Nasal Septal Perforation

+

   
Poor Dentition

+

   
Bruxism

+

   
Diaphoresis

+

   
Chest Pain

+

+

 
Nausea, Vomiting
 

+

 
Muscle Spasms

+

   
Clonus
   

+

Seizures

+

+

+

Psychosis
Agitation
Hallucinations

+

+

+

 

LABORATORY FINDINGS

Acute Kidney Injury
 

+

 
Acute Hepatitis

+

+

+

Rhabdomyolysis

+

 

+

 

 


Source: Weaver MF. Addict Sci Clin Pract. 2015 Mar 25;10:8.(pdf)


Please do post your questions or comments below. 


Dr. Harvinder Singh, M.D. (Admin)


Enroll in our online course to have access to all important clinically relevant psychiatry topics in one place.


Related Articles