Borderline Personality Disorder: Most Reliable Clinical Feature?

Q: Presence of Which Single Clinical Feature Identifies Most Patients with Borderline Personality Disorder and Absence of Which Rules out this Disorder?

Answer: Affective Instability.

Zimmermen et al evaluated 3674 psychiatric out-patients with a semi-structured diagnostic interview for DSM-IV borderline personality disorder (BPD) and found:-

  • Affective instability criterion had a sensitivity of 92.8%, higher than the sensitivities of the other eight BPD criteria.
  • The negative predictive value of the affective instability criterion was 99%.



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Dr. Harvinder Singh, M.D. (Admin)

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