Antipsychotics of Choice in Breast Cancer

Antipsychotics of Choice in Breast Cancer

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Special consideration is required when prescribing antipsychotic drugs for patients with an existing diagnosis of breast cancer. 

In general, first generation antipsychotics causes significant elevations in serum prolactin levels.

 

Antipsychotics that Increases Prolactin (45 to >100 ng/ml) and
Should be AVOIDED in Patients with Breast Cancer:

  1. Risperidone
  2. Paliperidone
  3. Haloperidol

Antipsychotics that Increases Prolactin (20-50 ng/ml) and
Should be CAUTIONED in Patients with Breast Cancer:

  1. Olanzapine
  2. Iloperidone
  3. Lurasidone

Antipsychotics that Increases Minimal Prolactin and
Are PREFERRED in Patients with Breast Cancer:

  1. Ziprasidone
  2. Asenapine
  3. Quetiapine
  4. Clozapine

Antipsychotic that may Lower Prolactin and
is PREFERRED in Patients with Breast Cancer:

  1. Aripiprazole

Source: Am J Psychiatry 2014;171:616-621.


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Dr. Harvinder Singh, M.D. (Admin)


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