Antidepressants in Bipolar Disorder: Clinical Facts

 

Q.1: Monotherapy with Antidepressants is not recommended in patient with bipolar disorder. Which antidepressants are preferred in conjunction with mood stabilizer?

  • SSRIs (other than paroxetine)
  • Bupropion

 


Q.2: What is the recommended duration of treatment with antidepressants in bipolar disorder?

  • Discontinue antidepressants 6–8 weeks after full remission of depression

 


Q.3: You decided to add antidepressant with mood stabilizer in patient with bipolar disorder. Which antidepressants should be avoided for association with increased risk of manic switch?

  • Tricyclic antidepressants
  • Venlafaxine

 


Q.4: Antidepressants are not recommended in which subtypes of bipolar disorder?

  • Current mixed episode
  • History of rapid cycling

 


Source: Bipolar Disorders, 15: 1–44

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Dr. Harvinder Singh, M.D. (Admin)


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